Participate in Alzheimer's Research
There isn't a cure for Alzheimer's yet––but you can be the change that creates one. Observational studies and clinical trials are vital in discovering how best to mitigate and treat Alzheimer's disease. Whether you're affected by Alzheimer's or not, you can increase the chances of finding a solution. All trials and studies below are based in the Greater Los Angeles area.
DIAGNOSED WITH ALZHEIMER'S
GOAL and RAPID Studies
Participate in in-person procedures, including physical examination and cognitive testing, to identify factors that shape the route of cognitive decline and investigate treatment.
Length of Study: No end date; testing occurs annually, as long as participants remain willing
Eligibility Includes: Adults with symptoms of Alzheimer's Disease and Related Dementias; healthy friends/family
Location: Cedars-Sinai Medical Center
VHB937 Antibody Testing
Test the results of the VHB937, an antibody directed at the brain's immune cell receptors, and allow researchers to evaluate its effect on individuals with Alzheimer's.
Length of Study: > 72 weeks
Eligibility Includes: People ages 50-85 with Early Alzheimer's Disease; see website for more specific constraints
Location: UCLA Westwood
Masupirdine for Agitation Treatment
Help evaluate the potential of masupirdine, an orally administered drug focused on treating agitation and behavioral symptoms.
Length of Study: 12 weeks
Eligibility Includes: People aged 50-90 with Alzheimer's Disease; score between 8 to 24 on Mini-Mental State Examinationl; no other symptoms of agitation unrelated to Alzheimer's
Location: Mary S Easton Center UCLA; Leading Edge Research LA
AT RISK OF ALZHEIMER'S
Omega-3 Supplements and Alzheimer's Disease Risk
Help find the effectiveness of omega-3 supplements on preventative care for those with increased risk of Alzheimer's Disease.
Length of Study: To Be Disclosed
Eligibility Includes: People aged 55-80 with high blood pressure, high cholesterol, little exercise, or are overweight
Location: Keck School of Medicine Alzheimer's Disease Research Center
Email cic_341@usc.edu
Call (323) 442-0209
HEALTHY AND WITHOUT SYMPTOMS
Stress and Aging Study
Provide evidence to examine impact of brief instances of stress on biomarkers that behave differently for those with Alzheimer's Disease; involves blood draws.
Length of Study: To Be Disclosed
Eligibility Includes: People aged 18-30 or 50-65 weighing at least 110 pounds; no cognitive impairment or conditions preventing completion of stressful tasks; non-pregnant and non-lactating
Location: To Be Disclosed
Email alzstudy@usc.edu
CARING FOR INDIVIDUALS WITH ALZHEIMER'S
GOAL and RAPID Studies
Answer questions surrounding the physical, mental, and behavioral condition of an individual with Alzheimer's, alongside their test results, to identify factors of cognitive decline.
Length of Study: No end date; testing occurs annually, as long as participants remain willing
Eligibility Includes: Adults with symptoms of Alzheimer's Disease and Related Dementias; healthy friends/family
Location: Cedars-Sinai Medical Center
Evaluation of Sleep and Well-Being
Test the Care2Sleep sleep intervention program's effects on inflammation within caregivers.
Length of Study: Until August 2027
Eligibility Includes: Adult caregivers who live with an Alzheimer's patient; Pittsburgh Sleep Quality Index score >5 and Montreal Cognitive Assessment greater or equal to 23; no paid professionals
Location: UCLA; Veterans Affairs Greater LA Healthcare System; UCSD